2-chloro-N-ethylbenzamide → n-Ethyl-2-chloro-6-(ethenyldimethylsilyl)benzamide

HRID 610902

반응식

HRID 610902 반응식
[CH2:1]([NH:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2].[CH:13]([Si:15](Cl)([CH3:17])[CH3:16])=[CH2:14]>>[CH2:1]([NH:3][C:4](=[O:12])[C:5]1[C:10]([Si:15]([CH:13]=[CH2:14])([CH3:17])[CH3:16])=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2]

참가 물질

3

반응물 2

HCID 3479622-chloro-N-ethylbenzamideHCID 519368Chloro(dimethyl)vinylsilane

생성물 1

HCID 18630374n-Ethyl-2-chloro-6-(ethenyldimethylsilyl)benzamide

실험 절차

The title compound was prepared from the compound of Example f and 1.5 eq vinyldimethylsilyl chloride according to General Method C. Purification by HPLC with 1:4 ethyl acetate/hexanes gave 630 mg of the desired product as a white solid, a 9% yield. m.p. 86-89° C.

후처리

  1. customPurification by HPLC with 1:4 ethyl acetate/hexanes

출처 및 근거

ORD 기록
ord-d8dad76c522c4ff1b01b78564ab1f2e6
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998466

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