Hydrochloric Acid → 4,5,6,7-Tetrahydrofuro[2,3-c]pyridine hydrochloride

HRID 611054노트

반응식

HRID 611054 반응식
C(OC([N:8]1[CH2:13][CH2:12][C:11]2[CH:14]=[CH:15][O:16][C:10]=2[CH2:9]1)=O)(C)(C)C.[ClH:17]>CO>[ClH:17].[O:16]1[C:10]2[CH2:9][NH:8][CH2:13][CH2:12][C:11]=2[CH:14]=[CH:15]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 11424602tert-Butyl 4,7-dihydrofuro[2,3-c]pyridine-6(5H)-carboxylate

생성물 1

HCID 195999074,5,6,7-Tetrahydrofuro[2,3-c]pyridine hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of 5.324 g (23.85 mmol) of 6-tert-butoxycarbonyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine in 100 ml of methanol, 5 ml of concentrated hydrochloric acid was added, followed by stirring at room temperature for 1 hour. The solvent was distilled off under reduced pressure to yield the desired product.

후처리

  1. distillationThe solvent was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-f77f909810404d96a4ab11341ffd9def
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

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