Hydrochloric Acid → N,N-dimethyl-[5-(6-phenylhexyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine dihydrochloride

HRID 611081노트

반응식

HRID 611081 반응식
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:26]>CO>[ClH:26].[ClH:26].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 19600160N,N-Dimethyl-[5-(6-phenylhexyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl)amine

생성물 1

HCID 19600159N,N-dimethyl-[5-(6-phenylhexyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine dihydrochloride

시약·촉매·용매 1

HCID 887Methanol용매2회

실험 절차

N,N-Dimethyl-[5-(6-phenylhexyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl)amine 0.199 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

후처리

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

출처 및 근거

ORD 기록
ord-a4752d186eb04f1ca66c0b5ac188ad8e
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

반응 노트

불러오는 중…