Hydrochloric Acid → HCID 19600238, 화합물

HRID 611150노트

반응식

HRID 611150 반응식
[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:28]>CO.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 19600003HCID 19600003, 화합물

생성물 1

HCID 19600238HCID 19600238, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 8857Ethyl Acetate용매

실험 절차

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-(4-fluorophenyl)hexan-1-one 0.098 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was washed with diethyl ether to yield the desired product.

후처리

  1. concentrationAfter this mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

출처 및 근거

ORD 기록
ord-6068050c85114646850f3e70977a81df
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

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