Hydrochloric Acid → (E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611346

반응식

HRID 611346 반응식
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:29])/[C:15](/[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:16]/[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:29])/[C:15](/[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:16]/[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 19600147(E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine

생성물 1

HCID 19600146(E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

시약·촉매·용매 2

HCID 887Methanol용매HCID 8857Ethyl Acetate용매

실험 절차

(E)-N,N-Dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.241 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.

후처리

  1. concentrationThis mixture was concentrated
  2. washwashed with diethyl ether

출처 및 근거

ORD 기록
ord-1c20908060a24e9a8f283d8a87b7543b
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

연결된 노트

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