Hydrochloric Acid → N,N-dimethyl-[6-(4-phenethylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611352노트

반응식

HRID 611352 반응식
[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 19600027N,N-dimethyl-[6-(4-phenethylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

생성물 1

HCID 19600126N,N-dimethyl-[6-(4-phenethylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

시약·촉매·용매 2

HCID 887Methanol용매HCID 8857Ethyl Acetate용매

실험 절차

N,N-Dimethyl-[6-(4-phenethylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.498 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.

후처리

  1. concentrationThis mixture was concentrated
  2. washwashed with diethyl ether

출처 및 근거

ORD 기록
ord-86aa7b241b37414d85e57ec3909e48f8
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

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