3-Butyn-2-ol → Undec-8-en-3-yne-2,5-diol

HRID 61344

반응식

HRID 61344 반응식
[CH3:1][CH:2]([OH:5])[C:3]#[CH:4].C([Mg]Br)C.[CH:10](=[O:17])[CH2:11][CH2:12][CH:13]=[CH:14][CH2:15][CH3:16]>O1CCCC1>[CH3:1][CH:2]([OH:5])[C:3]#[C:4][CH:10]([OH:17])[CH2:11][CH2:12][CH:13]=[CH:14][CH2:15][CH3:16]

참가 물질

5

반응물 3

HCID 162393-Butyn-2-olHCID 71590Hept-4-enalHCID 178418443HCID 178418443, 화합물

생성물 1

HCID 123300045Undec-8-en-3-yne-2,5-diol

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

But-3-yn-2-ol was added into a solution of ethyl magnesium bromide (EtMgBr) in tetrahydrofuran (THF). Hept-4-enal was then dropped into the mixture at room temperature and aged for 2 hours. The rush over process provided the product undec-8-en-3-yne-2,5-diol.

출처 및 근거

ORD 기록
ord-031d4fef6cf0407a9a44ce165221682a
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09441185B2

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