Hydrochloric Acid → HCID 178492409, 화합물

HRID 613954

반응식

HRID 613954 반응식
[NH2:1][C:2]1[C:3]([OH:12])=C2[C:8](=[N:9][C:10]=1[CH3:11])[NH:7][N:6]=N2.[CH3:13][N:14](C)C1C=CC=CC=1.[CH3:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]=[N:31][C:32]2[CH:40]=[C:36]([C:37](Cl)=[O:38])[C:35]([OH:41])=[CH:34][CH:33]=2)=[CH:26][CH:25]=1.Cl>CN(C)C=O>[OH:41][C:35]1[CH:34]=[CH:33][C:32]([N:31]=[N:30][C:27]2[CH:28]=[CH:29][C:24]([O:23][CH3:22])=[CH:25][CH:26]=2)=[CH:40][C:36]=1[C:37]([NH:1][C:2]1[C:10]([CH3:11])=[N:9][C:8]2[N:7]([N:6]=[CH:13][N:14]=2)[C:3]=1[OH:12])=[O:38]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 949N,N-DimethylanilineHCID 1355740405-(4-Methoxyphenylazo)salicoyl chlorideHCID 178432419HCID 178432419, 화합물

생성물 1

HCID 178492409HCID 178492409, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

5-Amino-4-hydroxy-6-methyltetraazaindene (0.5 g) was dissolved in dry N,N-dimethylformamide (10 ml) and dimethylaniline (0.37 g) added. 5-(4-Methoxyphenylazo)salicoyl chloride (0.88 g) was added portionwise at room temperature with stirring. After 12 hours the mixture was poured into iced dilute hydrochloric acid and the crude product collected, washed with water and dried. The material was extracted with a large volume of ether and crystallized in aqueous ethanol as the monohydrate (0.8 g, 61%), m.p. 323°-324° decomp., λmax (methanol) = 354 nm.

후처리

  1. customthe crude product collected
  2. washwashed with water
  3. customdried
  4. extractionThe material was extracted with a large volume of ether
  5. customcrystallized in aqueous ethanol as the monohydrate (0.8 g, 61%), m.p. 323°-324° decomp., λmax (methanol) = 354 nm

출처 및 근거

ORD 기록
ord-a4ee5ce9d0df4926b44ee18bc694f457
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04142901

연결된 노트

불러오는 중…