Nitric Acid → 3-Bromo-2-nitro-1-benzofuran

HRID 614358

반응식

HRID 614358 반응식
[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1.[N+:11]([O-])([OH:13])=[O:12].N([O-])=O.[Na+]>CO>[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[N+:11]([O-:13])=[O:12]

참가 물질

5

반응물 3

HCID 944Nitric Acid2회HCID 6405893-Bromo-1-benzofuranHCID 23668193Sodium Nitrite

생성물 1

HCID 135098423-Bromo-2-nitro-1-benzofuran

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A 5.0 g. sample of powdered 3-bromobenzofuran on a glass dish is placed next to a container of nitric acid. Sodium nitrite is added periodically to the nitric acid, and the entire experiment is covered with a bell jar. After about 15 minutes the powder becomes an oil. After 12 hours the product is dissolved in hot methanol and slowly crystallized by cooling. Recrystallization from methanol provides yellow crystals of 3-bromo-2-nitrobenzofuran, m.p. 130°-132° C. (lit. 132° C.).

후처리

  1. customslowly crystallized
  2. temperatureby cooling
  3. customRecrystallization from methanol

출처 및 근거

ORD 기록
ord-e8b879d8638c47dbba8295506a30c2d9
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04144347

연결된 노트

불러오는 중…