Sodium Hydroxide → Spiro(cyclopentane-1,2'(1'H)-(1,3,5)triazino(1,2-a)benzimidazol)-4'(3'H)-one, 3'-methyl-
반응식
CNC([N:5]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[N:7]2[C:14](=[O:23])[N:15]([CH3:22])[C:16]3([N:21]=[C:6]12)[CH2:20][CH2:19][CH2:18][CH2:17]3)=O.[OH-].[Na+]>C1COCC1>[CH3:22][N:15]1[C:16]2([CH2:20][CH2:19][CH2:18][CH2:17]2)[NH:21][C:6]2=[N:5][C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[N:7]2[C:14]1=[O:23]참가 물질
4
실험 절차
The reaction product of Example 26 was hydrolyzed by 10% aqueous sodium hydroxide and THF to give the title compound, employing the procedure of Example 1, paragraph 2. The product was recrystallized from acetone to give a solid, mp 180°-182° C. The confirmatory elemental analysis is shown in Table III.
출처 및 근거
- ORD 기록
- ord-361df454535740fdb7be749e27cfde28
- 출처 데이터셋
- uspto-grants-1985_02
- 특허 번호
- US04497650
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