Formaldehyde → N-phenylmethoxymethanimine

HRID 615311노트

반응식

HRID 615311 반응식
[CH2:1]=O.Cl.[CH2:4]([O:11][NH2:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[OH-].[Na+]>O>[CH2:4]([O:11][N:12]=[CH2:1])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

참가 물질

5

반응물 3

HCID 712FormaldehydeHCID 14798Sodium HydroxideHCID 102312Benzyloxyamine hydrochloride

생성물 1

HCID 561610N-phenylmethoxymethanimine

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

37% Formaldehyde (11.7 mL) was added to a slurry of benzyloxyamine hydrochloride (25.0 g, 0.156 mole) in 50 mL H2O. NaOH (6.3 g) in 25 mL H2O was then added over 20 minutes. The temperature rose to 40°. After stirring 2 hours, the reaction mixture was extracted 1×100 mL and 2×25 mL of ether. The ether extracts were combined, washed 2×50 mL saturated NaHCO3 and then 2×50 mL brine, dried and evaporated to yield title product as an oil, 20.0 g b.p. 195.5°.

후처리

  1. customrose to 40°
  2. extractionthe reaction mixture was extracted 1×100 mL and 2×25 mL of ether
  3. washwashed 2×50 mL saturated NaHCO3
  4. dry with material2×50 mL brine, dried
  5. customevaporated

출처 및 근거

ORD 기록
ord-e131f603a37c4381982b537df0273337
출처 데이터셋
uspto-grants-1985_02
특허 번호
US04499017

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