Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → N-(Butan-2-yl)-N-methyl-1-phenylisoquinoline-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | N-Methyl-2-butanamine | HCID 111026 | — |
| 반응물 | 1-Phenylisoquinoline-3-carboxylic acid | HCID 407896 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | N-(Butan-2-yl)-N-methyl-1-phenylisoquinoline-3-carboxamide | HCID 13272363 | 63.5% |
반응 단계
Operations are carried out as for Example 7, starting with 2.96 g of 1-phenyl isoquinoline 3-carboxylic acid, 1.33 g of triethylamine, 1.49 g of ethyl chloroformate and 1.34 g of N-methyl 2-butanamine in 120 ml of chloroform. 2.4 g of N-methyl N(1-methyl propyl) 1-phenyl isoquinoline 3-carboxamide melting at 95°-96° C., are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04499094 |
| 출처 데이터셋 | uspto-grants-1985_02 |
| ORD ID | ord-b729fd781ac7454fb621227a888506ed |
| 출처 메모 | uspto-grants-1985_02 |