Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dibutylamine → N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dibutylamine | HCID 8148 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 1-Phenylisoquinoline-3-carboxylic acid | HCID 407896 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide | HCID 20427637 | 41.5% |
반응 단계
Operations are carried out as for Example 7, starting from 2.5 g of 1-phenyl isoquinoline 3-carboxylic acid, 1.15 g of triethylamine, 1.24 g of ethyl chloroformate and 1.66 g of dibutylamine in 100 ml of toluene. After chromatography and recrystallization in petroleum ether, 1.5 g of N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide melting at 62° C. is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04499094 |
| 출처 데이터셋 | uspto-grants-1985_02 |
| ORD ID | ord-f1d271207d2244c4886c1a155473a2b5 |
| 출처 메모 | uspto-grants-1985_02 |