Dibutylamine → 2-Amino-5-dibutylamino-1,3,4-thiadiazole
반응식
[CH2:1]([NH:5][CH2:6][CH2:7][CH2:8][CH3:9])[CH2:2][CH2:3][CH3:4].C(N(CC)CC)C.[NH2:17][C:18]1[S:19][C:20](Cl)=[N:21][N:22]=1>C(O)C>[NH2:17][C:18]1[S:19][C:20]([N:5]([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:1][CH2:2][CH2:3][CH3:4])=[N:21][N:22]=1참가 물질
5
실험 절차
28 parts of dibutylamine and 25 parts of triethylamine are added to 27 parts of 2-amino-5-chloro-1,3,4-thiadiazole in 200 parts of ethanol. The reaction mixture is heated under reflux for 2 hours and then concentrated to dryness. The residue is suspended in 250 ml of water and filtered. The 2-amino-5-dibutylamino-1,3,4-thiadiazole obtained in this manner can be recrystallised from ethanol/water.
후처리
- temperatureThe reaction mixture is heated
- temperatureunder reflux for 2 hours
- concentrationconcentrated to dryness
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-e4d9ea73aa874bd6898361318cde9df6
- 출처 데이터셋
- uspto-grants-1985_02
- 특허 번호
- US04500715
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