Hydrochloric Acid → Methyl-3-(3,4-dihydro-4-ureido-1(2H)-Naphthylidene)carbazate

HRID 616055노트

반응식

HRID 616055 반응식
O=[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]([NH:12][C:13]([NH2:15])=[O:14])[CH2:4][CH2:3]1.[C:16]([O:20][CH3:21])(=[O:19])[NH:17][NH2:18].Cl>C(O)C>[CH3:21][O:20][C:16](=[O:19])[NH:17][N:18]=[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]([NH:12][C:13]([NH2:15])=[O:14])[CH2:4][CH2:3]1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 80519Methyl carbazateHCID 3628438Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

생성물 1

HCID 70627261Methyl-3-(3,4-dihydro-4-ureido-1(2H)-Naphthylidene)carbazate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 1,2,3,4-tetrahydro-4-oxo-1-naphthylurea (4.5 g), methyl carbazate (4.0 g), 95% ethanol (150 ml) and concentrated hydrochloric acid (2 ml) is heated at reflux for an overnight period. The mixture is cooled to room temperature and the crystals are collected. The product melts at 230° C to 233° C (dec). On recrystallizing from aqueous methanol, the title compound melts at 223° C to 225° C (dec).

후처리

  1. temperatureis heated
  2. temperatureat reflux for an overnight period
  3. customthe crystals are collected
  4. customOn recrystallizing from aqueous methanol

출처 및 근거

ORD 기록
ord-80d95cd0ef3d4a34bcd8a254501e139c
출처 데이터셋
uspto-grants-1978_02
특허 번호
US04072711

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