Acetic Anhydride → 1-Acetyl-6-nitroindole-3-carboxaldehyde

HRID 618113

반응식

HRID 618113 반응식
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([C:8]([CH:13]=[O:14])=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[C:15]([N:10]1[C:11]2[C:7](=[CH:6][CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:12]=2)[C:8]([CH:13]=[O:14])=[CH:9]1)(=[O:17])[CH3:16]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 52100766-nitro-1H-indole-3-carbaldehyde

생성물 1

HCID 218502221-Acetyl-6-nitroindole-3-carboxaldehyde수율 93.3%

실험 절차

Substantially the same procedure as in Example 3 was repeated using 6-nitroindole-3-carboxaldehyde (2.3 g) and acetic anhydride (2.47 g) to give 1-acetyl-6-nitroindole-3-carboxaldehyde (2.62 g).

출처 및 근거

ORD 기록
ord-ba69cd7ef1d048d68c244a66a899dc65
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05952355

연결된 노트

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