Lithium Bromide → 4-(Bromomethyl)-1-methyl-2-nitrobenzene
반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1.[Br-:13].[Li+]>CC(C)=O>[Br:13][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1참가 물질
4
실험 절차
4-Chloromethyl-1-methyl-2-nitro-benzene (5 g) was dissolved in 50 ml of acetone and 23.4 g of lithium bromide was added. The reaction mixture was heated at reflux for 18 hr. The solvent was evaporated off and the residue was tritrated with hexane to give 5.3 g of 4-bromomethyl-1-methyl-2-nitro-benzene as a tan solid. ##STR109##
후처리
- temperatureThe reaction mixture was heated
- temperatureat reflux for 18 hr
- customThe solvent was evaporated off
출처 및 근거
- ORD 기록
- ord-773fee99717c4e479dc308d5aca10c38
- 출처 데이터셋
- uspto-grants-1999_09
- 특허 번호
- US05952362
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