1,2-Epoxydodecane → HCID 21845238, 화합물

HRID 619099

반응식

HRID 619099 반응식
[O:1]=[S:2]1(=[O:15])[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)[CH2:4][CH2:3]1.[CH2:16]([CH:26]1[CH2:28][O:27]1)[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>[Br-].C([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)C>[O:15]=[S:2]1(=[O:1])[CH2:3][CH2:4][N:5]([C:8]2[CH:9]=[CH:10][C:11]([O:14][CH2:28][CH:26]([OH:27])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[CH:12][CH:13]=2)[CH2:6][CH2:7]1

참가 물질

4

반응물 2

HCID 178581,2-EpoxydodecaneHCID 218452234-(4-Hydroxyphenyl)thiomorpholine 1,1-Dioxide

생성물 1

HCID 21845238HCID 21845238, 화합물수율 38.9%

시약·촉매·용매 1

HCID 73727Phosphonium, ethyltriphenyl-, bromide (1:1)촉매

실험 절차

4-(1,1-dioxo-thiomorpholin-4-yl)phenol (2.3 g, 10 mmol), 2-(decyl)-oxirane (1.9 g, 10 mmol) and ethyltriphenylphosphonium bromide (0.2 g) are reacted and purified as described for compound 102 to afford a light browm solid 1.6 g (38%), m.p. 84° C.

후처리

  1. custompurified

출처 및 근거

ORD 기록
ord-baab20b918d040c59e85127047e616ec
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05958663

연결된 노트

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