Benzoyl Peroxide → 4-(Benzoxazol-2-yl)benzyl bromide

HRID 6210

반응식

HRID 6210 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[Br:17]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:17][CH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 700392-p-Tolylbenzoxazole

생성물 1

HCID 110335154-(Benzoxazol-2-yl)benzyl bromide

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매2회

실험 절차

A stirred solution of 20.9 g (0.1 mole) of 2-(4-methylphenyl)benzoxazole, 17.8 g (0.1 mole) of N-bromosuccinimide, and 0.4 g (0.2 mole %) of benzoyl peroxide in carbon tetrachloride is heated at reflux for 20 hours. After cooling to room temperature, the reaction is diluted by the addition of carbon tetrachloride, and the solid byproducts are removed by filtration. The filtrate is concentrated in vacuo, and the product is purified by recrystallization from benzene.

후처리

  1. temperatureat reflux for 20 hours
  2. customthe solid byproducts are removed by filtration
  3. concentrationThe filtrate is concentrated in vacuo
  4. customthe product is purified by recrystallization from benzene

출처 및 근거

ORD 기록
ord-5c4084f677714fefb5da04262b23b483
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05247042

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