Methyl iodide → HCID 88521502, 화합물

HRID 622315

반응식

HRID 622315 반응식
[CH3:1][CH2:2][O:3][C:4]([C:6]1[N:10]([CH:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])[CH:9]=[N:8][CH:7]=1)=[O:5].[I:19][CH3:20]>ClCCl>[I-:19].[CH2:2]([O:3][C:4]([C:6]1[NH+:10]([CH:11]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH3:12])[CH2:9][N:8]([CH3:20])[CH:7]=1)=[O:5])[CH3:1]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 36339Ethnor

생성물 1

HCID 88521502HCID 88521502, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a stirred solution of 7 parts of R-(+) ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate in 19.5 parts of iodomethane were added 21.3 parts of dichloromethane and the whole was stirred for 24 hours at room temperature. The reaction mixture was evaporated and the residue was crystallized from 2-propanol. The product was filtered off and washed with petroleum ether, yielding 7.03 parts of 5-ethoxycarbonyl-3-methyl-1-(1-phenylethyl)-1H-imidazolium iodide; mp. 159.5° C.; [α]D =-62.79° (10% water).

후처리

  1. customThe reaction mixture was evaporated
  2. customthe residue was crystallized from 2-propanol
  3. filtrationThe product was filtered off
  4. washwashed with petroleum ether

출처 및 근거

ORD 기록
ord-47aabe38e2c64e22973abf66b181e665
출처 데이터셋
uspto-grants-1988_09
특허 번호
US04770689

연결된 노트

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