Hydrochloric Acid → 3-Methoxyiminopyrrolidine hydrochloride
반응식
[ClH:1].C(OC([N:9]1[CH2:13][CH2:12][C:11](=[N:14][O:15][CH3:16])[CH2:10]1)=O)(C)(C)C.CCOCC>C(OCC)(=O)C>[ClH:1].[CH3:16][O:15][N:14]=[C:11]1[CH2:12][CH2:13][NH:9][CH2:10]1참가 물질
5
반응 조건
- 온도
- 40 °C
실험 절차
7 ml of a 3M hydrogen chloride solution in ethyl acetate was added to 2.3 g of ice-cooled 1-(t-butoxycarbonyl)-3-methoxyiminopyrrolidine, and the mixture was stirred at about 40° C. for one hour. After completion of the reaction, the solvent was stripped off from the reaction mixture and ether was added to the residue. The crystals which formed were collected by filtration and washed with ether, giving 1.5 g of the title compound.
후처리
- customAfter completion of the reaction
- additionwas added to the residue
- customThe crystals which formed
- filtrationwere collected by filtration
- washwashed with ether
출처 및 근거
- ORD 기록
- ord-717408610b5640e58a55825510da26e4
- 출처 데이터셋
- uspto-grants-1988_09
- 특허 번호
- US04771046
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