Water → Bromoethynyl triisopropylsilane

HRID 623671

반응식

HRID 623671 반응식
C1C(=O)N([Br:8])C(=O)C1.[CH:9]([Si:12]([C:19]#[CH:20])([CH:16]([CH3:18])[CH3:17])[CH:13]([CH3:15])[CH3:14])([CH3:11])[CH3:10].CCCCC.O>CC(C)=O.[N+]([O-])([O-])=O.[Ag+]>[Br:8][C:20]#[C:19][Si:12]([CH:13]([CH3:14])[CH3:15])([CH:9]([CH3:11])[CH3:10])[CH:16]([CH3:18])[CH3:17]

참가 물질

7

반응물 4

HCID 962WaterHCID 8003PentaneHCID 67184N-bromobutanimideHCID 2734682(Triisopropylsilyl)acetylene

생성물 1

HCID 11196280Bromoethynyl triisopropylsilane

시약·촉매·용매 2

HCID 24470Silver Nitrate촉매HCID 180Acetone용매

실험 절차

NBS (2.14 g, 12 mmol) and AgNO3 (170 mg, 1 mmol) were added to a solution of triisopropylsilylacetylene (2.24 ml, 10 mmol) in acetone (15 ml). The solution was stirred for 2 hours at RT. Pentane (20 ml) and H2O (20 ml) were added and the solution was stirred for 30 minutes. The organic phase was extracted with pentane (3×20 ml) and dried over Na2SO4. The solvent was removed under reduced pressure at RT and the residue was used in the next reaction without any purification.

후처리

  1. stirringthe solution was stirred for 30 minutes
  2. extractionThe organic phase was extracted with pentane (3×20 ml)
  3. dry with materialdried over Na2SO4
  4. customThe solvent was removed under reduced pressure at RT
  5. customthe residue was used in the next reaction without any purification

출처 및 근거

ORD 기록
ord-087145f8e7ff4a7eb7f1c6f990882090
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09302998B2

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