1,3-Cyclohexanedione → 2-[(Dimethylamino)methylidene]cyclohexane-1,3-dione
반응식
[C:1]1(=[O:8])[CH2:6][CH2:5][CH2:4][C:3](=[O:7])[CH2:2]1.[CH3:9][N:10]([CH:12](OC)OC)[CH3:11]>>[CH3:9][N:10]([CH:12]=[C:2]1[C:3](=[O:7])[CH2:4][CH2:5][CH2:6][C:1]1=[O:8])[CH3:11]참가 물질
3
반응 조건
- 온도
- 100 °C
실험 절차
A mixture of cyclohexane-1,3-dione (33.6 g, 300 mmol) in DMF-DMA (120 ml) was heated to 100° C. and stirred for 1 h under nitrogen protection. The volatiles were concentrated under reduced pressure. The red solid (55 g crude) was used in the next step directly.
후처리
- concentrationThe volatiles were concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-319371bbf428486bba88b1ed7d3dd6cb
- 출처 데이터셋
- uspto-grants-2016_09
- 특허 번호
- US09446130B2
반응 노트
불러오는 중…