1-Methylimidazole → Ethyl 2-(4-bromo-2-fluorophenyl)-1-(2-hydroxyethyl)-1H-imidazole-4-carboxylate
반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:9][CH:10]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:12]=2)=[C:4]([F:18])[CH:3]=1.[O:19]1[CH2:23][CH2:22]OC1=O.CN1C=CN=C1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]([CH2:22][CH2:23][OH:19])[CH:10]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:12]=2)=[C:4]([F:18])[CH:3]=1참가 물질
4
실험 절차
Ethyl 2-(4-bromo-2-fluorophenyl)-1H-imidazole-4-carboxylate 26 and 1,3-dioxolan-2-one and N-methylimidazole were reacted to give 27.
출처 및 근거
- ORD 기록
- ord-ae879755a56f477c910695c3422ecf07
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09303043B2
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