2-[(2-Nitrophenyl)sulfanyl]benzoic acid → 2-((2-Aminophenyl)thio)benzoic acid

HRID 625174

반응식

HRID 625174 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14])([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14]

참가 물질

4

반응물 1

HCID 3769782-[(2-Nitrophenyl)sulfanyl]benzoic acid

생성물 1

HCID 109558282-((2-Aminophenyl)thio)benzoic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

To a solution of 2-((2-nitrophenyl)thio)benzoic acid, prepared as described in the previous step, (43.3 g, 0.157 mol) in ethyl acetate (500 mL) was added Pd/C (8 g). The reaction solution was stirred at room temperature overnight under hydrogen gas atmosphere. The mixture was filtered and concentrated to provide the title compound.

후처리

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-91e47b447afe49b2be3082fc09c284fa
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09304126B2

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