Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl chloroformate → phenyl 1-m-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl chloroformate | HCID 15891 | — |
| 반응물 | 1-m-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-amine | HCID 66876804 | — |
| 생성물 | phenyl 1-m-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate | HCID 66876129 | 58% |
반응 단계
Following the procedure in Example 118A, 1-m-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (380 mg, 1.58 mmol) and phenyl chloroformate (0.60 mL, 4.74 mmol) were reacted to give phenyl 1-m-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate (330 mg, 0.91 mmol, 58%). 1H NMR (300 MHz, DMSO-d6) δ 10.4 (br s, 1H), 7.62-6.85 (m, 10H), 2.46 (s, 3H); LC-MS (ESI) m/z 362 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09320739B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-eff5608bdd2a4a36ac25383d348a07f4 |
| 출처 메모 | uspto-grants-2016_04 |