HCID 86674754, 화합물 → 2-Amino-2-ethyl-N-methyl-butyramide

HRID 632079노트

반응식

HRID 632079 반응식
[CH3:1][NH:2][C:3]([C:5]([NH:10]C(=O)OC(C)(C)C)([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4]>Cl.C(OCC)(=O)C>[NH2:10][C:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3]([NH:2][CH3:1])=[O:4]

참가 물질

4

반응물 1

HCID 86674754HCID 86674754, 화합물

생성물 1

HCID 798103702-Amino-2-ethyl-N-methyl-butyramide수율 75%

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 8857Ethyl Acetate용매

실험 절차

A mixture of tert-butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate (0.18 g, 0.74 mmol) in 10 ml saturated hydrochloride in ethyl acetate was stirred for 60 min at room temperature. Then the solution was evaporated to dryness to obtain the product (80 mg, 75%) as a light yellow solid; MS (LC/MS): 145.2 [M+H]+.

후처리

  1. customThen the solution was evaporated to dryness

출처 및 근거

ORD 기록
ord-c87266b78f9b4f709056706310a5c905
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09321727B2

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