반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:18]([NH:20][C:21]([CH2:29][CH3:30])([CH2:27][CH3:28])[C:22]([O:24]CC)=[O:23])=[O:19])=[N:8][C:9]=2[CH2:10][C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH2:3][CH2:2]1.[OH-].[Na+]>>[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:18]([NH:20][C:21]([CH2:29][CH3:30])([CH2:27][CH3:28])[C:22]([OH:24])=[O:23])=[O:19])=[N:8][C:9]=2[CH2:10][C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH2:3][CH2:2]1참가 물질
3
실험 절차
In analogy to the procedure described in Example 252 b), ethyl 2-(5-cyclopropyl-6-(4-fluorobenzyl)picolinamido)-2-ethylbutanoate was treated with sodium hydroxide to give the title compound as white solid. MS: 383.3 [M−H]−.
출처 및 근거
- ORD 기록
- ord-5286cfbe432c4ad4a92f1d5c7e39380c
- 출처 데이터셋
- uspto-grants-2016_04
- 특허 번호
- US09321727B2
연결된 노트
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