Stannous Chloride → 3-Allyloxycarbonyl-5-aminobenzamide

HRID 635394노트

반응식

HRID 635394 반응식
[CH2:1]([O:4][C:5]([C:7]1[CH:8]=[C:9]([CH:13]=[C:14]([N+:16]([O-])=O)[CH:15]=1)[C:10]([NH2:12])=[O:11])=[O:6])[CH:2]=[CH2:3].Cl[Sn]Cl>>[CH2:1]([O:4][C:5]([C:7]1[CH:8]=[C:9]([CH:13]=[C:14]([NH2:16])[CH:15]=1)[C:10]([NH2:12])=[O:11])=[O:6])[CH:2]=[CH2:3]

참가 물질

3

반응물 2

HCID 24479Stannous ChlorideHCID 221685603-Allyloxycarbonyl-5-nitrobenzamide

생성물 1

HCID 221686283-Allyloxycarbonyl-5-aminobenzamide수율 56.8%

실험 절차

3-Allyloxycarbonyl-5-nitrobenzamide (1 g) was reduced with SnCl2 by a similar method to the reduction in example 12, giving 3-allyloxycarbonyl-5-aminobenzamide (0.5 g). Nmr (DMSO-d6): 4.78 (dt, 2H); 5.2-5.8 (broad, 2H); 5.26-5.45 (m, 2H); 5.91-6.13 (m, 1H); 7.22 (broad s, 1H); 7.27 (t, 1H); 7.33 (t, 1H); 7.59 (s, 1H).

출처 및 근거

ORD 기록
ord-7e91d48b27e741529a539e63f11f3e65
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187804B1

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