Methanol → HCID 15382693, 화합물

HRID 635497

반응식

HRID 635497 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:13]([NH:21][C:22]1[C:23]2[N:24]=[CH:25][N:26]([C:35]=2[N:36]=[CH:37][N:38]=1)[C@@H:27]1[O:34][C@H:31]([CH2:32][OH:33])[C@@H:29]([OH:30])[CH2:28]1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CO>N1C=CC=CC=1>[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([O:33][CH2:32][C@H:31]2[O:34][C@@H:27]([N:26]3[C:35]4[N:36]=[CH:37][N:38]=[C:22]([NH:21][C:13](=[O:20])[C:14]5[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=5)[C:23]=4[N:24]=[CH:25]3)[CH2:28][C@@H:29]2[OH:30])=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

5

반응물 3

HCID 887MethanolHCID 85024-Nitrobenzoyl chlorideHCID 107558N-benzoyl-2'-deoxyadenosine

생성물 1

HCID 15382693HCID 15382693, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매2회

실험 절차

The synthesis of this product is carried out by reacting 1 eq of p-nitrobenzoyl chloride with 6-N-benzoyldeoxyadenosine for 4 hours in pyridine. After hydrolysis of the excess reagent, partial evaporation of the pyridine, extraction and evaporation of the chloroformic phase, the product is obtained by column chromatography (elution 4% methanol).

후처리

  1. customThe synthesis of this product
  2. customfor 4 hours

출처 및 근거

ORD 기록
ord-5abaca9d871242a3abe42dc791ab9001
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06187914B1

연결된 노트

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