6-Azaindole → 3-(1,2,3,5,8,8a-Hexahydro-7-indolizinyl)-1H-6-azaindole
반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[N:7][CH:8]=2)[CH:3]=[CH:2]1.[NH:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1>C(O)C>[CH2:13]1[CH:14]2[N:10]([CH2:2][CH:3]=[C:4]([C:3]3[C:4]4[C:9](=[CH:8][N:7]=[CH:6][CH:5]=4)[NH:1][CH:2]=3)[CH2:5]2)[CH2:11][CH2:12]1참가 물질
4
실험 절차
from 6-azaindole (250 mg, 2.1 mmol), 1,2,3,5,6,8,8a-heptahydrohydro-7-oxo-indolizine (324 mg, 2.3 mmol) and pyrrolidine (1.2 g, 16.9 mmol) in ethanol (2 mL) heating at reflux for 6 hrs.
후처리
- temperatureat reflux for 6 hrs
출처 및 근거
- ORD 기록
- ord-9350e5429e8c4d0bab3bd432cb2e3f02
- 출처 데이터셋
- uspto-grants-2001_02
- 특허 번호
- US06191141B1
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