Benzenesulfonyl chloride → HCID 70224336, 화합물

HRID 636804노트

반응식

HRID 636804 반응식
[O:1]=[C:2]1[N:6]([CH2:7][CH:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[C:5](=[CH:14][C:15]([C:17]2[CH:24]=[CH:23][C:20]([C:21]#[N:22])=[CH:19][CH:18]=2)=[O:16])[NH:4][C:3]1([CH2:32][C:33]1[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=1)[CH2:25][C:26]1[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=1.[C:39]1([S:45](Cl)(=[O:47])=[O:46])[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[C:39]1([S:45]([N:11]2[CH2:12][CH2:13][CH:8]([CH2:7][N:6]3[C:2](=[O:1])[C:3]([CH2:25][C:26]4[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=4)([CH2:32][C:33]4[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=4)[NH:4][C:5]3=[CH:14][C:15]([C:17]3[CH:18]=[CH:19][C:20]([C:21]#[N:22])=[CH:23][CH:24]=3)=[O:16])[CH2:9][CH2:10]2)(=[O:47])=[O:46])[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1

참가 물질

3

반응물 2

HCID 7369Benzenesulfonyl chlorideHCID 70225437HCID 70225437, 화합물

생성물 1

HCID 70224336HCID 70224336, 화합물

실험 절차

According to the procedure of Example 13, the title compound of 40B (50 mg, 0.099 mmol) and benzenesulfonyl chloride (0.025 ml, 0.198 mmol) were reacted to generate the title compound as a white solid (25 mg, 0.037 mmol, 37% yield).

출처 및 근거

ORD 기록
ord-1375db9bd279485aab9f68a0a9a2c229
출처 데이터셋
uspto-grants-2001_02
특허 번호
US06194438B1

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