3-Hydroxypyridine → 5-Benzyloxy-2-methoxyphenacyl 3-Methoxvphenyl Ether
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.OC1C=NC=CC=1.[CH2:17]([O:24][C:25]1[CH:26]=[CH:27][C:28]([O:35][CH3:36])=[C:29]([CH:34]=1)[C:30](=[O:33])[CH2:31]Br)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([O:9][CH2:31][C:30]([C:29]2[CH:34]=[C:25]([O:24][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:26]=[CH:27][C:28]=2[O:35][CH3:36])=[O:33])[CH:6]=[CH:7][CH:8]=1참가 물질
4
실험 절차
By the method of Example 1, substituting a molar equivalent of 3-methoxyphenol for 3-hydroxypyridine, 5-benzyloxy-2-methoxyphenacyl bromide was converted to present title product; mp 76°-77° C.; IR (KBr) 1680 cm-1 ; MS 378 (M+); Anal. C 73.05, H 5.74, calcd. C 73.00, H 5.86.
출처 및 근거
- ORD 기록
- ord-d914eb82cf014fdb8c3669a45bdd545d
- 출처 데이터셋
- uspto-grants-1993_09