3-Hydroxypyridine → 5-Benzyloxy-2-methoxyphenacyl 3-Methoxvphenyl Ether

HRID 6373

반응식

HRID 6373 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.OC1C=NC=CC=1.[CH2:17]([O:24][C:25]1[CH:26]=[CH:27][C:28]([O:35][CH3:36])=[C:29]([CH:34]=1)[C:30](=[O:33])[CH2:31]Br)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([O:9][CH2:31][C:30]([C:29]2[CH:34]=[C:25]([O:24][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:26]=[CH:27][C:28]=2[O:35][CH3:36])=[O:33])[CH:6]=[CH:7][CH:8]=1

참가 물질

4

반응물 3

HCID 79713-HydroxypyridineHCID 90073-MethoxyphenolHCID 148556125-Benzyloxy-2-methoxyphenacyl bromide

생성물 1

HCID 148830015-Benzyloxy-2-methoxyphenacyl 3-Methoxvphenyl Ether

실험 절차

By the method of Example 1, substituting a molar equivalent of 3-methoxyphenol for 3-hydroxypyridine, 5-benzyloxy-2-methoxyphenacyl bromide was converted to present title product; mp 76°-77° C.; IR (KBr) 1680 cm-1 ; MS 378 (M+); Anal. C 73.05, H 5.74, calcd. C 73.00, H 5.86.

출처 및 근거

ORD 기록
ord-d914eb82cf014fdb8c3669a45bdd545d
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05248685

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