Aluminum Stearate → Apraclonidine
반응식
C([O-])(=O)CCCCCCCCCCCCCCCCC.[Al+3].C([O-])(=O)CCCCCCCCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCCCCCCCC.[CH2:62]1[NH:66][C:65]([NH:67][C:68]2[C:73]([Cl:74])=[CH:72][C:71]([NH2:75])=[CH:70][C:69]=2[Cl:76])=[N:64][CH2:63]1.Cl.Cl>>[CH2:62]1[NH:66][C:65]([NH:67][C:68]2[C:73]([Cl:74])=[CH:72][C:71]([NH2:75])=[CH:70][C:69]=2[Cl:76])=[N:64][CH2:63]1참가 물질
3
반응 조건
- 온도
- 115 °C
실험 절차
The aluminum stearate was dispersed with stirring in a portion of the sunflower oil heated to 115° C. The dispersion was added to the rest of the sunflower oil heated to 140° C. The gel was stirred at 130° C. for 15 minutes and then allowed to cool without stirring to room temperature. The milled p-Amino Clonidine dihydrochloride was dispersed in the cooled gel base and then passed through a colloid mill to produce a fine, homogenous dispersion. The dispersion was filled into plastic bottles fitted with a dosing pump.
후처리
- additionThe dispersion was added to the rest of the sunflower oil