Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 3-Amino-1-(4-methoxyphenyl)but-2-en-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | 1-(4-Methoxyphenyl)butane-1,3-dione | HCID 77640 | — |
| 생성물 | 3-Amino-1-(4-methoxyphenyl)but-2-en-1-one | HCID 1517163 | — |
| 생성물 | 4-Methoxyphenyl-1-methyl-3-oxo-1-propenamine | HCID 86740567 | — |
반응 단계
The intermediate 3-(4-methoxyphenyl)-1-methyl-3-oxo-1-propenamine was prepared as follows: A mixture containing 106 g of 1-(4-methoxyphenyl)-1,3-butanedione, 500 ml of methanol and 200 ml of concentrated aqueous ammonium hydroxide was allowed to stand at room temperature for 4 hours and then chilled in a refrigerator. The separated crystalline product was collected, washed with ether and dried at 90°-95° C. to yield 93.7 g of 3-(4-methoxyphenyl-1-methyl-3-oxo-1-propenamine, m.p. 126°-128° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04560691 |
| 출처 데이터셋 | uspto-grants-1985_12 |
| ORD ID | ord-20a53e81f4a4421c83d3b5634084ecbb |
| 출처 메모 | uspto-grants-1985_12 |