Potassium Carbonate → CF3Cfhcf2CH2ocf2cfhocf3

HRID 638682

반응식

HRID 638682 반응식
FC(F)(C)C(F)(F)C(F)(F)O.[C:12]([CH:16]([C:18]([CH2:21][OH:22])([F:20])[F:19])[F:17])([F:15])([F:14])[F:13].C(=O)([O-])[O-].[K+].[K+].[C:29]([O:33][C:34](=[C:36]([F:38])[F:37])[F:35])([F:32])([F:31])[F:30]>C(#N)C>[C:12]([CH:16]([C:18]([CH2:21][O:22][C:36]([CH:34]([O:33][C:29]([F:32])([F:31])[F:30])[F:35])([F:38])[F:37])([F:20])[F:19])[F:17])([F:15])([F:14])[F:13]

참가 물질

6

반응물 4

HCID 11430Potassium CarbonateHCID 14474Perfluoro(methyl vinyl ether)HCID 5339902,2,3,4,4,4-Hexafluorobutan-1-olHCID 216527211,1,2,2,3,3-Hexafluorobutan-1-ol

생성물 1

HCID 131728025CF3Cfhcf2CH2ocf2cfhocf3

시약·촉매·용매 1

HCID 6342Acetonitrile용매

반응 조건

온도
45 °C

실험 절차

Hexafluorobutanol, CF3CFHCF2CH2OH (65.3 g, 0.34 mol), prepared essentially as described in Example 2) was combined with potassium carbonate (9.9 g, 0.072 mol) and 133 g of acetonitrile in a 600 mL Parr reactor. The temperature of the reactor was raised to 45° C. and CF3OCF═CF2 (65.6 g, 0.39 mol) added as a gas over about two hours. The resulting reaction mixture was stirred for about 18 hours at 45° C. The reactor was cooled and the contents of the reactor filtered to remove the potassium carbonate. The resulting product-containing filtrate was distilled using a concentric tube column, with the product cut boiling at 115-119° C. The product structure was confirmed by GCMS.

후처리

  1. customThe resulting reaction mixture
  2. temperatureThe reactor was cooled
  3. filtrationthe contents of the reactor filtered
  4. customto remove the potassium carbonate
  5. additionThe resulting product-containing filtrate
  6. distillationwas distilled

출처 및 근거

ORD 기록
ord-1c1bafd3df174d5992769608d611e75f
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07691282B2

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