Ethanol → HCID 23080034, 화합물

HRID 63871

반응식

HRID 63871 반응식
C(O)C.[Br:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([CH:15]=O)=[CH:7][CH:6]=1.Cl.[NH2:18][OH:19].C([O-])(=O)C.[Na+]>O>[Br:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8](/[CH:15]=[N:18]/[OH:19])=[CH:7][CH:6]=1

참가 물질

6

반응물 4

HCID 702EthanolHCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium AcetateHCID 46404134-Bromo-1-naphthaldehyde

생성물 1

HCID 23080034HCID 23080034, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Into a 250-mL round-bottom flask, was placed ethanol (100 mL), water (40 mL), 4-bromonaphthalene-1-carbaldehyde (4.3 g, 18.29 mmol, 1.00 equiv), hydroxylamine hydrochloride (1.52 g, 21.87 mmol, 1.20 equiv), sodium acetate (2.25 g, 27.43 mmol, 1.50 equiv). The resulting solution was stirred for 2 h at room temperature. The resulting mixture was concentrated under vacuum. The solids were collected by filtration and washed with enough water. The solid was dried in an oven under reduced pressure. This resulted in 4.5 g (98%) of (E)-N-[(4-bromonaphthalen-1-yl)methylidene]hydroxylamine as a white solid.

후처리

  1. customInto a 250-mL round-bottom flask, was placed
  2. concentrationThe resulting mixture was concentrated under vacuum
  3. filtrationThe solids were collected by filtration
  4. washwashed with enough water
  5. customThe solid was dried in an oven under reduced pressure
  6. customThis resulted in 4.5 g (98%) of (E)-N-[(4-bromonaphthalen-1-yl)methylidene]hydroxylamine as a white solid

출처 및 근거

ORD 기록
ord-5c26ee1119f740c48a0fa8b649b90420
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09447084B2

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