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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 642394생성일: 2026년 10월 26일

1-Benzyl-1H-pyrazole-4-boronic acid → 2-(1-Benzyl-1h-pyrazol-4-yl)-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642394

반응식

참여 물질

역할이름HCID투입량
반응물1-Benzyl-1H-pyrazole-4-boronic acidHCID 3352881—
반응물2-Bromo-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethyl esterHCID 68426454—
생성물2-(1-Benzyl-1h-pyrazol-4-yl)-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethyl esterHCID 68428356—

반응 단계

Prepared from 2-bromo-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethy ester, example 81(b), and 1-benzyl-1H-pyrazole-4-boronic acid under conditions analogous to experimental example 81(c). MS: (+) m/z 579.4 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07696223B2
출처 데이터셋uspto-grants-2010_04
ORD IDord-aa1431426e2943b1ae653397f8acf1d7
출처 메모uspto-grants-2010_04