Glycine → HCID 68426196, 화합물

HRID 642444노트

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HRID 642444 반응식
C(O[C:4]([C:6]1[C:7]([OH:24])=[C:8]2[C:16]([Cl:17])=[CH:15][N:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:9]2=[C:10]([C:12]#[N:13])[N:11]=1)=[O:5])C.[NH2:25][CH2:26][C:27]([OH:29])=[O:28].C[O-].[Na+].CO>>[Cl:17][C:16]1[C:8]2[C:9](=[C:10]([C:12]#[N:13])[N:11]=[C:6]([C:4]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:5])[C:7]=2[OH:24])[N:14]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:15]=1

참가 물질

4

반응물 3

HCID 750GlycineHCID 23694274Sodium methanolate methanolHCID 684285233-chloro-7-cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

생성물 1

HCID 68426196HCID 68426196, 화합물

실험 절차

Prepared in analogy to that of Example 1(e) from 3-chloro-7-cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 369 (M−1)−.

출처 및 근거

ORD 기록
ord-98ea55ce53344ac1ab915afc73a6f2e8
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07696223B2

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