Acetic Anhydride → 4-Acetoxy-7-cyano-1-(4-methoxy-phenyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

HRID 642490노트

반응식

HRID 642490 반응식
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:26])=[C:8]2[CH:16]=[CH:15][N:14](CC3C=CC(OC)=CC=3)[C:9]2=[C:10]([C:12]#[N:13])[N:11]=1)=[O:5])[CH3:2].[C:27]([O:30][C:31](=O)[CH3:32])(=O)C>C(N(CC)CC)C>[CH2:1]([O:3][C:4]([C:6]1[C:7]([O:26][C:1](=[O:3])[CH3:2])=[C:8]2[CH:16]=[CH:15][N:14]([C:6]3[CH:4]=[CH:32][C:31]([O:30][CH3:27])=[CH:8][CH:7]=3)[C:9]2=[C:10]([C:12]#[N:13])[N:11]=1)=[O:5])[CH3:2]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 68428970HCID 68428970, 화합물

생성물 1

HCID 684261564-Acetoxy-7-cyano-1-(4-methoxy-phenyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

Prepared in analogy to that of Example 120(a) from 7-cyano-4-hydroxy-1-(4-methoxy-benzyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, acetic anhydride, and triethyl amine. The title compound, ESI MS (m/z): 380 (M+H)+.

출처 및 근거

ORD 기록
ord-d2bf9ec03009446382a6d4be382295d0
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07696223B2

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