2',4'-Dichloroacetophenone → 4-(2,4-Dichlorophenyl)-1,3-thiazol-2-amine

HRID 644470

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=O)[CH3:10].[NH2:12][C:13]([NH2:15])=[S:14]>>[NH2:15][C:13]1[S:14][CH:10]=[C:9]([C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])[N:12]=1

참가 물질

반응물 2

HCID 166932',4'-Dichloroacetophenone

HCID 2723790Thiourea

생성물 1

HCID 7042374-(2,4-Dichlorophenyl)-1,3-thiazol-2-amine수율 97.1%

실험 절차

Using 2′,4′-dichloroacetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.

출처 및 근거

ORD 기록: ord-1c7d5cc0f332413cb2fb9865bccd3f8f
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07700655B2

연결된 노트

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