Ethanone, 1-(3,4-dichlorophenyl)- → 4-(3,4-Dichlorophenyl)-1,3-thiazol-2-amine

HRID 644476노트

반응식

HRID 644476 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[CH3:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:12][C:13]([NH2:15])=[S:14]>>[NH2:15][C:13]1[S:14][CH:10]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[N:12]=1

참가 물질

3

반응물 2

HCID 75841Ethanone, 1-(3,4-dichlorophenyl)-HCID 2723790Thiourea

생성물 1

HCID 6185364-(3,4-Dichlorophenyl)-1,3-thiazol-2-amine수율 77.8%

실험 절차

Using 3′,4′-dichloroacetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.

출처 및 근거

ORD 기록
ord-752602b229294cc0b5f5d115b8abdf1b
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07700655B2

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