1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime → 1'-Methyl-2,3-dihydrospiro[indene-1,4'-piperidin]-3-amine

HRID 645599노트

반응식

HRID 645599 반응식
CO[N:3]=[C:4]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:6]2([CH2:11][CH2:10][N:9]([CH3:12])[CH2:8][CH2:7]2)[CH2:5]1>[Ni]>[CH3:12][N:9]1[CH2:8][CH2:7][C:6]2([C:13]3[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:4]([NH2:3])[CH2:5]2)[CH2:11][CH2:10]1

참가 물질

3

반응물 1

HCID 860822791'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime

생성물 1

HCID 685844981'-Methyl-2,3-dihydrospiro[indene-1,4'-piperidin]-3-amine

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

The product of Example 138C and Raney/nickel were processed according to the method of Example 131C to provide the product. MS (ESI+) m/z 217 (M+H)+.

후처리

  1. customto provide the product

출처 및 근거

ORD 기록
ord-b36b6a65671c4cc89de24cc5ed7ab8ac
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07704997B1

반응 노트

불러오는 중…