Pyridine → Allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate

HRID 64579

반응식

HRID 64579 반응식
[CH2:1]([OH:4])[CH:2]=[CH2:3].N1C=CC=CC=1.[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=[CH:13][C:12]=1[O:21][C:22]1[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28](Cl)=[O:29])=[CH:24][CH:23]=1>C(Cl)Cl>[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=[CH:13][C:12]=1[O:21][C:22]1[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28]([O:4][CH2:1][CH:2]=[CH2:3])=[O:29])=[CH:24][CH:23]=1

참가 물질

5

반응물 3

HCID 1049PyridineHCID 7858Allyl AlcoholHCID 136705322-[4-(2-Quinoxalinyloxy)phenoxy]propionyl chloride

생성물 1

HCID 13670534Allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

To a solution of 1.2 g allyl alcohol and 1.6 g pyridine in 50 cc methylene chloride, add 6.6 g of 2-[4-(2-quinoxalinyloxy)phenoxy]propionyl chloride in 60 cc methylene chloride. Stir the mixture at room temperature overnight. Wash the methylene chloride solution with water and dry the solution over magnesium sulfate concentrate under vacuum to give allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate.

후처리

  1. washWash the methylene chloride solution with water
  2. dry with materialdry the solution over magnesium sulfate
  3. concentrationconcentrate under vacuum

출처 및 근거

ORD 기록
ord-a9135ae31a7f4357adf017005813a8cd
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04609396

연결된 노트

불러오는 중…