4-Bromophenol → 1-Bromo-4-(2-methylpropoxy)benzene

HRID 646107노트

반응식

HRID 646107 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.I[CH2:10][CH:11]([CH3:13])[CH3:12].[OH-].[Na+]>CN(C=O)C>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 78084-BromophenolHCID 10556Isobutyl iodideHCID 14798Sodium Hydroxide

생성물 1

HCID 153241111-Bromo-4-(2-methylpropoxy)benzene수율 19.5%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

4-bromophenol (2.4 g, 13.8 mmol), 1-iodo-2-methylpropane (3.45 mL, 20 mmol), sodium hydroxide (0.8 g, 20 mmol) and DMF (2 mL) were allowed to react to yield the sub-title compound (615 mg, 19%).

후처리

  1. customto react

출처 및 근거

ORD 기록
ord-47a34356242e46739ddb6a8245673667
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07705023B2

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