3,4-Dichloroaniline → Triclocarban

HRID 648074

반응식

HRID 648074 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=O)[O:10]C)=[CH:4][CH:3]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][C:20]=1[Cl:21])[NH2:17].CN(CCCCCCCCCCCC)C>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:17][C:16]2[CH:18]=[CH:19][C:20]([Cl:21])=[C:14]([Cl:13])[CH:15]=2)=[O:10])=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 72573,4-DichloroanilineHCID 8168LauryldimethylamineHCID 70326Carbamic acid, (4-chlorophenyl)-, methyl ester

생성물 1

HCID 7547Triclocarban

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A mixture of 4.61 g (25 mmoles) of methyl N-(4-chlorophenyl)-carbamate, 4.07 g (25 mmoles) of 3,4-dichloroaniline, 100 ml of toluene and 4.7 g (25 mmoles) of N,N-dimethyl-dodecylamine is reacted for 20 hours as described in Example 8, and then the mixture is allowed to cool. 4.60 g (58.4%) of N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)-urea separate from the mixture as a crystalline substance.

후처리

  1. customis reacted for 20 hours
  2. temperatureto cool
  3. custom4.60 g (58.4%) of N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)-urea separate from the mixture as a crystalline substance

출처 및 근거

ORD 기록
ord-3ac25ca201324c0788c4c6c1d1ae9148
출처 데이터셋
uspto-grants-1983_10
특허 번호
US04410697

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