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Chloroform → HCID 20484710, 화합물

HRID 648078
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HRID 648078 반응식
[CH:1]1([S:7]Cl)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:9]1([NH:15][S:16]([C:19]2[S:20][C:21]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:22]=3[N:23]=2)(=[O:18])=[O:17])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.C(N(CC)CC)C.C(Cl)(Cl)Cl>CN(C)C=O>[CH:1]1([S:7][N:15]([CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)[S:16]([C:19]2[S:20][C:21]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:22]=3[N:23]=2)(=[O:17])=[O:18])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 6212ChloroformHCID 8471TriethylamineHCID 87312Cyclohexanesulfenyl chlorideHCID 20484714HCID 20484714, 화합물

생성물 1

HCID 20484710HCID 20484710, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

2.6 grams of cyclohexyl chlorosulfide (0.0172 mole) prepared as in Example 1 is added slowly to a stirred solution containing 5.4 grams (0.0163 mole) of N-cyclohexyl-5-chlorobenzothiazole-2-sulfonamide, and 2 grams of triethylamine (0.0178 mole) in 150 ml anhydrous dimethylformamide. The temperature is maintained between about 15° and 20° C. After stirring, 100 ml of chloroform is added and the reaction mixture is poured into 2 liters of ice water, and treated as in Example 5.

후처리

  1. additionis added slowly to a stirred solution
  2. temperatureThe temperature is maintained between about 15° and 20° C
  3. additiontreated as in Example 5

출처 및 근거

ORD 기록
ord-67e97946bb7c4a43908e3e7d4622ff84
출처 데이터셋
uspto-grants-1983_10
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04410704

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