Pyruvic Acid → N-acetylformyl,N-(4-chlorophenyl)valine

반응식

[C:1](O)(=[O:5])[C:2]([CH3:4])=[O:3].[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([NH:14][C@H:15]([C:19]([OH:21])=[O:20])[CH:16]([CH3:18])[CH3:17])=[CH:10][CH:9]=1>>[C:2]([C:1]([N:14]([C:11]1[CH:10]=[CH:9][C:8]([Cl:7])=[CH:13][CH:12]=1)[C@H:15]([C:19]([OH:21])=[O:20])[CH:16]([CH3:18])[CH3:17])=[O:5])(=[O:3])[CH3:4]

참가 물질

반응물 2

HCID 1060Pyruvic Acid

HCID 13796078N-(p-chlorophenyl)valine

생성물 1

HCID 57070001N-acetylformyl,N-(4-chlorophenyl)valine

실험 절차

Following the procedure of Example 47, the m-phenoxybenzyl ester of N-acetylformyl,N-(4-chlorophenyl)valine [MS m/e 479 (M+, 0.5), 183 (100)] is prepared by the reaction of the acid chloride of pyruvic acid with the m-phenoxybenzyl ester of N-(4-chlorophenyl)valine.

출처 및 근거

ORD 기록: ord-1c248e28888c405d8c6b39979172355a
출처 데이터셋: uspto-grants-1983_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04411912

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