2-Methoxyaniline → N-(2-methoxyphenyl)valine

반응식

[CH3:1][O:2][C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].C(OC1C=CC(N)=CC=1)C.Br[CH:21]([CH:39]([CH3:41])[CH3:40])[C:22]([O:24]CC1C=CC=C(OC2C=CC=CC=2)C=1)=[O:23]>>[CH3:1][O:2][C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH:5][C@H:21]([C:22]([OH:24])=[O:23])[CH:39]([CH3:41])[CH3:40]

참가 물질

반응물 3

HCID 70002-Methoxyaniline

HCID 90764-Ethoxyaniline

HCID 13229492m-Phenoxybenzyl alpha-bromoisovalerate

생성물 1

HCID 15383895N-(2-methoxyphenyl)valine

실험 절차

Using the procedure of Example 1, each of 2-methoxyaniline and 4-ethoxyaniline is reacted with m-phenoxybenzyl α-bromoisovalerate to yield the m-phenoxybenzyl ester of N-(2-methoxyphenyl)valine, MS m/e 405.2 (M+), and the m-phenoxybenzyl ester of N-(4-ethoxyphenyl)valine, MS m/e 419.1 (M+).

출처 및 근거

ORD 기록: ord-15434e297a9b45e1923b130b3d0f1024
출처 데이터셋: uspto-grants-1983_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04411912

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