Acetic Anhydride → HCID 20145181, 화합물

HRID 648640노트

반응식

HRID 648640 반응식
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>>[C:29]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1)(=[O:31])[CH3:30]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 20145241HCID 20145241, 화합물

생성물 1

HCID 20145181HCID 20145181, 화합물

실험 절차

An amount of 0.10 gm (0.262 m mol) of 4-[(1-(5-amino-2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid in 1 ml of acetic anhydride was stirred for six hours at 20° C., evaporated in vacuo, and distilled off several times with toluene, and the evaporation residue was recrystallized from ether.

후처리

  1. customevaporated in vacuo
  2. distillationdistilled off several times with toluene
  3. customthe evaporation residue was recrystallized from ether

출처 및 근거

ORD 기록
ord-8bf896ff200b4485b23d43d618bb3e6c
출처 데이터셋
uspto-grants-1988_04
특허 번호
US04735959

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